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When a man kick of cold orflu symptom , it may not be fair to dismiss his laments as simply a case of " man flu . " Men may really experience worse symptoms than women after catching a respiratory computer virus , a new review suggests .
The review waspublished today(Dec . 11 ) in a special Christmas issue of the aesculapian journal The BMJ ; the holiday edition feature inquiry that is more light-hearted than the daybook ’s usual fare .

" Man flu " mention to the idea that men may exaggerate the symptom of a underage illness , such as a cold . Although the term is commonly used ( particularly in the United Kingdom ) , no scientific review so far has examined whether the term is appropriate or accurate , said Dr. Kyle Sue , a clinical help professor at Memorial University of Newfoundland in Canada , who authored the BMJ review .
In a search of the scientific literature , Sue find grounds that military man may have a weakerimmune responseto the viruses that cause flu or the common cold , and as a outcome , men may have a greater risk for serious symptoms , and even last , from these viruses . [ Men vs. fair sex : Our Key Physical Differences excuse ]
For example , a 2008 study establish that woman had a solid resistant reply to theflu vaccine , meaning they produced greater levels of antibody against the computer virus tense in the vaccine , liken with men .

Other study from Hong Kong and the United States have found that , compared with cleaning woman , men have a higher risk for infirmary price of admission anddeath from the grippe .
" The concept of man flu , as ordinarily defined , is potentially unfair , " Sue wrote in the paper . " Men may not be hyperbolize symptoms but have weak immune reaction to viral respiratory viruses , moderate to greater morbidness and mortality than seen in charwoman , " he said .
It ’s not clear why serviceman may have a weaker resistant reception to respiratory virus , but hormones could dally a role , with the " female"hormone estrogen , in exceptional , providing a protective effect against these virus , Sue said .

For exemplar , in a 2016 report , researchers expose manlike and female human nasal bone cells to estrogen in a lab dish aerial , and then infected the cell with the influenza virus . The researcher found that the estrogen reduce the levels of flu computer virus in the cells from female donors , but not male person donors .
What ’s more , other studies have suggested that the " male " hormonetestosteronemay lower the body ’s resistant answer to flu virus , Sue said .
Still , more research in this area is require , in part because some of the studies let in in the revue did not look at factors like smoke and preventive - charge visits , which could affect people ’s overall wellness and their power to respond to cold and influenza viruses , Sue say . The current inspection was not capable to include research on respiratory viruses that did not separate out the resultant role by sexual activity .

Some researchers have speculated that military man ’s apparently weaker resistant response to sealed viruses has an evolutionary explanation , Sue said . For our ancestors , the effects of testosterone ( i.e. , increase muscularity and pearl quite a little ) may have overbalance the likely immunosuppressive effect of the internal secretion , he say . ( More research , however , is require to examine this hypothesis . )
Sue also mark that there could be benefits to the extreme energy conservation that homo seem to require when afflicted with flu . " Lying on the couch , not get under one’s skin out of bed or incur aid with activity of daily living could also be evolutionarily behaviors that protect against vulture , " Sue wrote in his tongue - in - cheek termination . " Perhaps now is the time for male person - friendly space , equip with tremendous televisions and reclining chairs , to be go down up where men can recover from the debilitating effects of Isle of Man flu in rubber and comfortableness . "
Original clause onLive scientific discipline .















