Sharon Osbourne.Photo:David M. Benett/Getty

David M. Benett/Getty
Sharon Osbourneis one of the manycelebritieswho has publicly shared their experience taking Ozempic for weight loss. However, last weekThe Talk UKhost, 70, admitted that after dropping 42 lbs. she’s quitting the trendy medication because“I didn’t want to go this thin.”
Similarly,Shahs of SunsetalumGolnesa “GG” Gharachedaghisaid in June that she was“cutting back” on the drugafter losing “more weight than I was anticipating.”
Ozempicis an FDA-approved prescription medication for people with type 2 diabetes. It’s one of the brand names for semaglutide — also known asWegovyandMounjaro— which works in the brain to impact satiety, and is the latest Hollywood weight loss trend.
What are the side effects of Ozempic?
“It’s very important to always start at the lowest dose when you’re starting these medications and to go up slowly. If the medication is increased too quickly, then these side effects are more likely to occur,” Jastreboff added. “We also know that a majority of the side effects occur during that dose escalation phase.”
Ozempic injector.Getty

Getty
What happens when you stop taking Ozempic?
Although Osbourne successfully lost weight, she decided to ditch Ozempic. A study in theJournal of Pharmacology and Therapeuticsfound that a majority of people who take semaglutide gain most of the weight back within a year of stopping the medication, which can be difficult to control.
Jastreboff also told PEOPLE that because drugs like Ozempic and Wegovy are intended for type 2 diabetes and obesity — which are chronic conditions — they aren’t meant to be stopped.
“If you have a patient who has high blood pressure, they have hypertension, and you start them on an antihypertensive medication, and their blood pressure improves, what would happen if you stopped that medication? Well, their blood pressure would go back up — and we’re not surprised. It’s the same with anti-obesity medications,” she explained, adding that the drugs are not tested for people who do not have type 2 diabetes or chronic obesity.
Box of type 2 diabetes drug Ozempic.Mario Tama/Getty

Mario Tama/Getty
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“[Expecting a patient with chronic obesity to lose weight through willpower] is akin to having a patient with diabetes and thinking that they can concentrate really hard to bring their blood sugars down,” Jastreboff continued. “You can’t do that, and with obesity, our patients can’t use their prefrontal cortex for the rest of their lives to impact every morsel of food that they eat. So, it’s not in our control. Once that set point is elevated, you need treatment.”
Content creatorand modelRemi Baderpreviously shared that her weight rebounded after stopping Ozempic.
She explained that although she was able to lose weight from the medication in 2020, when she stopped taking it she “gained double the weight back,” adding that she thinks it really should just be used for those who need it medically.
Meanwhile, Osbourne admitted that expects something similar to happen to her, quipping, “I’ll probably put it all on again soon.”
source: people.com